Articles, Web Directory

Lymph Node Metastasis in Early Signet Ring Cell Carcinoma: Feasibility of Endoscopic Mucosal Resection

Thu, 17 Apr 2008 08:07:23 MST

Abstract Objective: To identify clinicopathological factors predictive of lymph node metastases (LNM) in early signet ring cell carcinoma (SRC), and further to expand the possibility of using endoscopic mucosal resection (EMR) for the treatment of early SRC. Methods: Data from 27 patients with early SRC and surgically treated were collected, and the association between the clinicopathological factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. Results: In the univariate analysis, a tumor larger than 3.0 cm, submucosal invasion, and the presence of lymphatic vessel involvement (LVI) were significantly associated with a higher rate of LNM (all P<0.05). In the multivariate model, the presence of LVI was found to be independently risk pathological factor for LNM. There was no LNM in 14 patients without the three risk clinicopathological factors (a tumor larger than 3.0 cm, submucosal invasion, and the presence of LVI). Conclusions: EMR alone may be sufficient treatment for intramucosal early SRC if the tumor is less than or equal to 3.0 cm in size, and when LVI is absent upon postoperative histological examination. When specimens shows with LVI, an additional radical gastrectomy with lymphadenectomy should be recommended. Key words: Early signet ring cell carcinoma; LNM; Clinicopathological characteristics; Endoscopic mucosal resection

Antiproliferation and colony-forming inhibition activities of ã- tocotrienol in human colon carcinoma HT-29 cells

Mon, 05 Nov 2007 05:56:39 MST

Recent data indicated that TRF (tocotrienol-rich fraction) could inhibit the cancer cells through affecting proliferation and apoptosis. In this study, the suppressing effect of ã- tocotrienol in human colon carcinoma HT-29 cell line was evaluated. Cell viability, colony formation and mitotic index were employeed in HT-29 cells treated with ã- tocotrienol at doses of (15, 30, 45, 60ìM).

Diet And Breast Cancer

Fri, 29 Dec 2006 17:15:48 MST

This article explores the link between food and breast cancer. It provides valuable information on the type of diet that can help breast cancer victims.

Can Breast Cancer be Prevented?

Mon, 18 Dec 2006 17:02:54 MST

Wise woman herbalist Susun Weed offers suggestions on whether breast cancer can be prevented.

Over Coming Breast Cancer

Mon, 18 Dec 2006 17:02:53 MST

Being diagnosed with breast cancer is one of the most scary things a woman can learn. We know a great deal about it because information on breast cancer is in just about every woman's magazine, alon...

Antioxidants and the Prevention of Breast Cancer

Mon, 18 Dec 2006 17:02:53 MST

So far, in 2006 alone, there have been over 212,000 new cases of invasive breast cancer diagnosed, as well as over 61,000 cases of non-invasive breast cancer. Over 40,000 women will die from breast ca...

What treatments are currently being used for victims of asbestos diseases?

Wed, 11 Oct 2006 20:11:59 MST

Mesothelioma is touted as deadly because most of the cases are diagnosed when in advanced stage and doctors have little solace to offer by then. Still doctors try to do their best to relieve the patients from severe pain of mesothelioma using advanced treatments.

What are some coping strategies found useful by mesothelioma victims?

Wed, 11 Oct 2006 19:56:40 MST

Coping with mesothelioma, unlike other types of cancer, can be significantly difficult. There are few support groups specifically available for mesothelioma. These are quite often informal groups of people who reside in the same area or who occasionally meet each other in doctors' chambers or hospital waiting rooms.

Two Substances That May Reduce the Risk Of Cancer

Wed, 11 Oct 2006 19:44:15 MST

Food helps us by supplying many vital micronutrients such as vitamins and minerals. Your genetic composition can make you susceptible to some types of cancer. Your way of eating plays a major role in increasing or reducing the risk of cancer.

Mesothelioma - The Disease that Strikes 40 Years Later

Tue, 10 Oct 2006 17:12:34 MST

Mesothelioma is a rare form of cancer in which malignant (cancerous) cells are found in the mesothelium, a protective sac that covers most of the body's internal organs. Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles.

Mesothelioma - Is Cancer Hibernating in You?

Tue, 10 Oct 2006 16:31:16 MST

Imagine a disease that lays eggs inside your lungs. These eggs do not produce discomfort or coughing, they don't cause outbreaks or rashes or anything of the sort. In fact these eggs don't do anything except sit in your lungs and germinate for 30 to 40 years.